We are your choice for the most advanced blood and marrow transplant care.

Our outcomes for treating damaged or destroyed bone marrow with healthy bone marrow stem cells are among the nation’s best. In fact, we are on a select national list of institutions that meet the highest standards in every aspect of stem cell therapy. 

There are three types of bone marrow transplants and treatments.

A bone marrow transplant is a procedure to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Bone marrow is the soft, fatty tissue inside your bones. Stem cells are immature cells in the bone marrow that give rise to all of your blood cells.

Autologous Bone Marrow Transplant

The term auto means self. Stem cells are removed from you before you receive high-dose chemotherapy or radiation treatment. The stem cells are stored in a freezer (cryopreservation). After high-dose chemotherapy or radiation treatments, your stem cells are put back in your body to make (regenerate) normal blood cells. This is called a rescue transplant.

Allogeneic Bone Marrow Transplant

The term allo means other. Stem cells are removed from another person, called a donor. Most times, the donor's genes must at least partly match your genes. Special blood tests are done to see if a donor is a good match for you. A brother or sister is most likely to be a good match. Sometimes parents, children, and other relatives are good matches. Donors who are not related to you may be found through national bone marrow registries.

Umbilical Cord Blood Transplant

This is a type of allogeneic transplant. Stem cells are removed from a newborn baby's umbilical cord right after birth. The stem cells are frozen and stored until they are needed for a transplant. Umbilical cord blood cells are very immature so there is less of a need for matching. But blood counts take longer to recover.

Transplant is a treatment for a variety of diseases.

Our experienced team has provided more than 4,000 stem cell transplants—adult, pediatric, allogeneic and autologous—since 1980.

Blood and marrow transplants may be part of the treatment plan for a variety of diseases, including:

  • Hodgkin lymphoma (HL)
  • Non-Hodgkin lymphoma (NHL)
  • Myelodysplastic/myeloproliferative diseases (MDS/MPN)
  • Acute myelogenous leukemia (AML)
  • Acute lymphoblastic leukemia (ALL)
  • Multiple myeloma/plasma cell disorder (PCD)
  • Solid tumors (ST), including certain types of sarcoma and tumors affecting the reproductive system and nervous system
  • Chronic myelogenous leukemia (CML)
  • Severe aplastic anemia (SAA)
  • Histiocytic disorders (HD)
  • Disorders of immune system (including auto-immune disorders)

The University of Iowa Blood and Marrow Transplant Program